[Posted 08/27/2009] Tibotec Therapeutics and FDA notified healthcare
professionals of revisions to the WARNINGS AND PRECAUTIONS section of
the prescribing information for Intelence (etravirine). There have been
postmarketing reports of cases of Stevens-Johnson syndrome, toxic
epidermal necrolysis and erythema multiforme, as well as
hypersensitivity reactions characterized by rash, constitutional
findings, and sometimes organ dysfunction, including hepatic failure.
Intelence therapy should be immediately discontinued when signs and
symptoms of severe skin or hypersensitivity reactions develop.
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